Nancy Yuk-Yu

PhD in Pharmacology
Vice-President for Research and Development
The Morningside Professor of Life Science
Chair Professor
Director of State Key Laboratory of Molecular Neuroscience
Research Interests
Selected Publications
Zhou, Xiaopu; Chen, Yu; Mok, Kin Ying Boniface; Zhao, Qianhua; Chen, Keliang; Chen, Yuewen; Hardy, John; Li, Yun; Fu, Kit Yu; Guo, Qihao; Ip, Nancy Yuk-yu, Identification of Genetic Risk Factors in The Chinese Population Implicates a Role of the Immune System in Alzheimer’s Disease Pathogenesis, 2018, Link
Xiao, Fang; Ng, Yu Pong; Tsim, Karl Wah Keung; Wise, Helen; Wong, Yung Hou; Ip, Nancy Yuk Yu; Wu, Zhenguo, Identification of critical early genes involved in nerve growth factor-induced PC12 differentiation, 2005, Link
Ho, Siu Hong; So, Lac Hue; Lai, Kwok On; Ip, Nancy Yuk Yu; Leung, Mun Fai, Induction of NG108-15 cells differentiation by human bone marrow stromal cells, 1998, Link
Fu, Amy Kit Yu; Smith, Frances D.; Zhou, Hong; Chu, Apple H.; Tsim, Karl Wah Keung; Peng, Benjamin H.; Ip, Nancy Y Y, Xenopus muscle-specific kinase: molecular cloning and prominent expression in neural tissues during early embryonic development, 1999, Link
Tang, H.B.; Ip, Nancy Y.Y., Biological and genetic therapy for brain injury, 1999, Link
Yang, JF; Zhou, H.; Choi, Roy Chi Yan; Ip, Nancy Yuk Yu; Peng, Benjamin Hsiao Ming; Tsim, Karl Wah Keung, A cysteine-rich form of Xenopus neuregulin induces the expression of acetylcholine receptors in cultured myotubes, 1999, Link
Fu, Amy Kit Yu; Cheung, Waiman; Ip, Fanny Chun Fun; Ip, Nancy Yuk Yu, Identification of genes induced by neuregulin in cultured myotubes, 1999, Link
Lai, Kwok On; Ip, Fanny Chun Fun; Ip, Nancy Yuk Yu, Identification and characterization of splice variants of ephrin-A3 and ephrin-A5, 1999, Link
Xie, Ping; Chan, Frances; Ip, Nancy Yuk Yu; Leung, MF, Induction of gp130 and LIF by differentiation inducers in human myeloid leukemia K562 cells, 1999, Link
Cheung, Waiman; Fu, Wing Yu; Hui, Wing S.; Ip, Nancy Yuk Yu, Production of human CNS neurons from embryonal carcinoma cells using a cell aggregation method, 1999, Link
Xie, Ping; Chan, Frances SL; Ip, Nancy Yuk Yu; Leung, Mun-Fai, Nerve growth factor potentiated the sodium butyrate- and PMA-induced megakaryocytic differentiation of K562 leukemia cells, 2000, Link
Ip, Nancy Y., Signaling through the ciliary neurotrophic factor receptor complex, 2005, Link
Liu, Lizz Y.X.; Cheng, Kai; Hung, Nelson K.W.; Fu, Amy K.Y.; Ip, Nancy Y., Pctaire1 phosphorylates N-ethylmaleimide sensitive fusion protein and regulates constitutive exocytosis in PC12 cells, 2005, Link
Ip, Fanny C.F.; An, Hui Jin; Chan, A.W.S.; Tong, Pui Sze; Hu, Sharry Y.; Wong, Yung Hou; Ip, Nancy Y.Y., Screening for NMDA receptor antagonists using traditional Chinese medicine, 2005, Link
Kam, Angel Yuet Fong; Yung, Ying; Wu, Eddy H.T.; Ng, Yu Pong; Wu, Zhenguo; Tsim, Karl Wah Keung; Wise, Helen; Ip, Nancy Yuk Yu; Wong, Yung Hou, Role of calmodulin-dependent kinase II in nerve growth factor-induced differentiation of PC12 cells., 2005, Link
Hung, Nelson K.W.; Shen, Winnie Y.; Fu, Amy K.Y.; Ip, Nancy Y., Identification of anaphase promoting complex subunit 2 isoform as EphA4 interacting protein, 2005, Link
Chen, Yu; Luo, Shuo; Lai, Kwok On; Arevalo, Juan C.; Froehner, Stanley C.; Adams, Marvin E.; Chao, Moses V.; Ip, Nancy Y., ARMS interacts with alpha-syntrophin: implications for the localization and signaling of EphA4 at the neuromuscular synapse, 2005, Link
Cheung, WMW; Ip, Nancy Yuk Yu, Interaction of neurotrophins and retinoic acid in neuronal differentiation, 1998, Link
Chao, L.C.F.; Ip, Nancy Y.Y., Hong Kong - An emerging hub for Traditional Chinese Medicine, 2000, Link
Tang, Huibin; Fu, Wing Yu; Ip, Nancy Yuk Yu, Altered expression of tissue-type plasminogen activator and type 1 inhibitor in astrocytes of mouse cortex following scratch injury in culture, 2000, Link
Tang, Huibin; Cheung, Waiman; Ip, Fanny Chun Fun; Ip, Nancy Yuk Yu, Identification and characterization of differentially expressed genes in denervated muscle, 2000, Link
Lao, Alex Ieng Kin; Lee, Thomas Ming Hung; Hsing, I. Ming; Ip, Nancy Yuk Yu, Precise temperature control of microfluidic chamber for gas and liquid phase reactions, 2000, Link
Ip, Fanny Chun Fun; Chung, SSK; Fu, Wing Yu; Ip, Nancy Yuk Yu, Developmental and tissue-specific expression of DEAD box protein p72, 2000, Link
Cheung, Waiman; Hui, Wing S.; Chu, Patrick; Chiu, Siuwai; Ip, Nancy Yuk Yu, Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells, 2000, Link
Xia, Youlin; Kong, Xiangming; Ip, Nancy Yuk Yu; Zhu, Guang, A J-multiplied HMQC (MJ-HMQC) experiment for measuring (3)J(HNH alpha) coupling constants, 2000, Link
Ip, Fanny Chun Fun; Glass, David G.; Gies, David R.; Cheung, Janet; Lai, Kwok On; Fu, Amy Kit Yu; Yancopoulos, GD; Ip, Nancy Yuk Yu, Cloning and characterization of muscle-specific kinase in chicken, 2000, Link
Ping, Xie; Chan, Frances; Ip, Nancy Yuk Yu; Leung, Munfai, IL-6 enhanced the retinoic acid-induced differentiation of human acute promyelocytic leukemia cells, 2000, Link
Cheung, Waiman; Chu, Patrick; Lung, Chuek H.; Ip, Nancy Yuk Yu, Expression of retinoid receptors during the retinoic acid-induced neuronal differentiation of human embryonal carcinoma cells, 2000, Link
Mei, Hua; Wu, Zhenguo; Ip, Nancy Yuk Yu; Wong, Yung Hou, Overexpression of Galphaz inhibits muscle differentiation, 2005, Link
Ng, Yu-Pong; He, Wei; Ip, Nancy Y., Leukemia inhibitory factor receptor signaling negatively modulates NGF-induced neurite outgrowth, 2003, Link
Fu, Amy K.Y.; Ng, Alberto K.Y.; Chien, Winnie W.Y.; Ng, Yu-Pong; Fu, Ada W.Y.; Wang, Jerry H.; Ip, Nancy Y., Cdk5 phosphorylates Stat3 and regulates its transcriptional activity, 2003, Link
Xu, Wen; Li, Jiong; Xue, Mei; Carles, Marias C.; Trau, Dieter; Lenigk, Ralf; Sucher, Nikolaus J.; Ip, Nancy Yuk Yu; Chan, Mansun, Surface characterization of DNA microarray on silicon dioxide and compatible silicon materials in the immobilization process, 2002, Link
Ip, Nancy Y., Characterization of the Interacting domains between the CNTF receptor and its beta receptor components, 2002, Link
Lai, Kwok On; Fu, Wing Yu; Ip, Fanny Chun Fun; Ip, Nancy Yuk Yu, Cloning and expression of a novel neurotrophin, NT-7, from carp, 1998, Link
Yang, Tie F.; Zhou, Hong; Pun, San; Ip, Nancy Y Y; Peng, H. Benjamin; Tsim, Karl Wah Keung, Cloning of cDNAs encoding Xenopus neuregulin: expression in myotomal muscle during embryo development, 1998, Link
Ip, Nancy Yuk Yu; Zigmond, R.E., Synergistic effects of muscarinic agonists and secretin or vasoactive intestinal peptide on the regulation of tyrosine hydroxylase activity in sympathetic neurons, 2000, Link
Waraksa, J.A.; Lindsay, R.M.; Ip, N.Y.; Hutz, R.J., Neurotrophin-3 augments steroid secretion by hamster ovarian follicles in vitro., 1995, Link
Ip, Fanny Chun Fun; Fu, Amy Kit Yu; Tsim, Karl Wah Keung; Ip, Nancy Yuk Yu, Differential expression of ciliary neurotrophic factor receptor in skeletal muscle of chick and rat after nerve injury, 1996, Link
Lai, Kwok On; Glass, DJ; Geis, D.; Yancopoulos, GD; Ip, Nancy Yuk Yu, Structural determinants of Trk receptor specificities using BDNF-based neurotrophin chimeras, 1996, Link
Cheung, WMW; Chu, AH; Leung, MF; Ip, Nancy Yuk Yu, Induction of trk receptors by retinoic acid in a human embryonal carcinoma cell line, 1996, Link
Ip, Fanny Chun Fun; Fu, Amy Kit Yu; Tsim, Karl Wah Keung; Ip, Nancy Yuk Yu, Cloning of the α component of the chick ciliary neurotrophic factor receptor: Developmental expression and down-regulation in denervated skeletal muscle, 1995, Link
Ip, NY; Yancopoulos, GD, Neurotrophic factors and their receptors, 1995, Link
DeChiara, T.M.; Vejsada, R.; Poueymirou, W.T.; Acheson, A.; Suri, C.; Conover, J.C.; Friedman, B.; McClain, J.; Pan, L.; Stahl, N.; Ip, N.Y.; Kato, A.; Yancopoulos, G.D., Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth, 1995, Link
Conover, J.C.; Erickson, J.T.; Katz, D.M.; Bianchi, L.M.; Poueymirou, W.T.; McClain, J.; Pan, L.; Helgren, M.; Ip, N.Y.; Boland, P.; Friedman, B.; Wiegsand, S.; Vejsada, R.; Kato, A.C.; DeChiara, T.M.; Yancopoulos, G.D., Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4, 1995, Link